Chloroquine has been around since 1984 and not 100 uyaers vas suggested by the ICMR. It has been used to treat malaria all these years but not Covid-19. The big Lancet observational study has documented increased death with hydroxychloroquine and chloroquine. The WHO has suspended HCQ in its SOLIDARITY trial. The French health ministry has outright banned use of HCQ. But the ICMR without any published data insist on touting the efficacy of HCQ in post exposure prophylaxis to prevent Covid-19.
Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis Mandeep R Mehra, Sapan S Desai, Frank Ruschitzka, Amit N Patel Published Online May 22, 2020 https://doi.org/10.1016/ S0140-6736(20)31180-6 ;The Lancet.
ARTICLE IN PRESS International Journal of Antimicrobial Agents xxx (xxxx) xxx Contents lists available at ScienceDirect International Journal of Antimicrobial Agents journal homepage: www.elsevier.com/locate/ijantimicag [m5G;April 25, 2020;22:47 ] Short Communication Can post-exposure prophylaxis for COVID-19 be considered as an outbreak response strategy in long-term care hospitals? Sun Hee Leea,1, Hyunjin Sonb,1, Kyong Ran Peckc.
medRxiv preprint doi: https://doi.org/10.1101/2020.05.19.20101832.this version posted May 22, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France Samira FAFI-KREMER1,2,*,, Timothée BRUEL3,*, Yoann MADEC4, Rebecca GRANT4, Laura TONDEUR4, Ludivine GRZELAK3,5, Isabelle STAROPOLI3, François ANNA6, Philippe SOUQUE7, Catherine SCHMIDT-MUTTER8, Nicolas COLLONGUES8,14, Alexandre BOLLE8, Aurélie VELAY1,2 , Nicolas LEFEBVRE9, Marie MIELCAREK10, Nicolas MEYER10,11, David REY 12, Pierre CHARNEAU6,7, Bruno HOEN13, Jérôme De SEZE8,14, Olivier SCHWARTZ3,** and Arnaud FONTANET4,15,**
medRxiv preprint doi: https://doi.org/10.1101/2020.04.30.20085613.this version posted May 5, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Humoral immune response and prolonged PCR positivity in a cohort of 1343 SARS-CoV 2 patients in the New York City region Authors: Ania Wajnberg MD, Mayce Mansour, MD, Emily Leven, MD, Nicole M. Bouvier, MD, Gopi Patel, MD, Adolfo Firpo, MD, Rao Mendu, PhD, Jeffrey Jhang, MD, Suzanne Arinsburg, DO, Melissa Gitman, MD MPH, Jane Houldsworth, PhD, Ian Baine, MD PhD, Viviana Simon, MD PhD, Judith Aberg, MD, Florian Krammer, PhD, David Reich, MD, Carlos Cordon-Cardo, MD, PhD Author affiliations: Icahn School of Medicine at Mount Sinai, New York NY